New research suggests that cannabinoids, such as THCV, CBDV and CBM, produced by marijuana and hemp, may help treat skin diseases like eczema, psoriasis and acne.
The study published in Molecules, a peer-reviewed journal this week, suggests that minor cannabinoids may hold therapeutic promise for the treatment of dermatological disease. Incorporating cannabinoids in dermatological treatments could offer patients novel treatment options and improve their well-being.
Researchers Emilia Kwiecien, Dorota Kwalczuk, reviewed the literature in scientific journals to reach these conclusions. They found that minor cannabinoids have a variety of pharmacological properties, such as anti-inflammatory, antimicrobial and anti-itch effects.
Some minor cannabinoids appeared to be particularly suited for treating certain diseases. The authors, for instance, wrote that “CBDV’s anti-inflammatory properties can be used to relieve skin symptoms like itching and swelling” in the treatment of atopic (AD). Cannabinoids, with their anti-inflammatory and antioxidant effects, may also have a healing affect on acne lesions.
The study goes on to say that “other cannabinoids, such as CBM or CBE, have also shown anti-inflammatory properties.” They represent a new alternative to conducting scientific research on specific diseases conditions. CBC may also have a positive impact on acne, psoriasis, and AD, due to its anti-inflammatory, antioxidant properties.
THCV “shows promising properties” in the fight against acne, as it could help regulate sebum. It also has “anti-inflammatory and antibiotic properties” that help reduce inflammation and fight the bacteria responsible for acne.
All told, researchers identified possible therapeutic applications of the minor cannabinoids CBDV (cannabidivarin), CBDP (cannabidiforol), CBC (cannabichromene), THCV (tetrahydrocannabivarin), CBGA (cannabigerolic acid), CBG (cannabigerol) and CBN (cannabinol), as well as more recently discovered cannabinoids CBM (cannabimovone) and CBE (cannabielsoin).
The study’s authors believe that the effects are the result of cannabinoids interfacing with the body’s “endocannabinoid” system, which is “a central regulator system responsible for maintaining health and proper function of almost every organism.” The study’s authors explain that “increasing evidence indicates that endocannabinoid signals play a critical role in regulating the biological processes of the skin.” The endocannabinoid systems regulates many skin functions such as immune response and cell proliferation.
The study found that topical application of minor cannabinoids could even help to mitigate the effects associated with aging.
The authors stressed that further research on minor cannabinoids is necessary “to confirm their safety and effectiveness,” but also acknowledged the fact that there are still obstacles to progress.
They wrote: “The impact of cannabinoids on the nervous system and issues related to product quality, regulation and ethical and legal considerations, including those pertaining legality, need comprehensive consideration.” The authors wrote: “Despite the promising therapeutic potential, the use of cannabinoids is required to be further researched, with regulations in place and a balanced strategy that ensures benefits while minimising health and social risks.”
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